Tumor Mutational Burden: Clinical and Diagnostic Utilization in Oncology


Lauren Ritterhouse MD, PhD


Susan Hsiao MD, PhD

This webinar is a recorded presentation of a live broadcast and includes the presentation, handout, and the audience QA.

Please note that this content was created in 2018. In the time since this material was posted, there may have been additional developments, advancements, and/or more current publications in this field.

AMP Education is constantly updating our educational offerings, and will remove or replace content that is no longer accurate. Please be sure to use the search function to find related or updated material available in our catalogue at educate.amp.org. The Training and Education Committee works with AMP Education Programs to bring you the most up-to-date and cutting-edge information on molecular pathology research, applications, and training.


This webinar will cover the background and rationale for the use of tumor mutational burden (TMB) as a biomarker for immunotherapy in oncology. The various biomarkers that have been evaluated for immunotherapy will be explored and a discussion of TMB’s role and use in oncology will be made. The course will cover an overview of immunotherapy drugs, targets, and tumor types for which TMB has been used as a biomarker.

Learning Objectives:

  • Define TMB and the rationale for its use as a biomarker for immunotherapy in oncology
  • Describe the clinical utilization of TMB in oncology

Recording Date: June 27, 2018
Duration: 1 hr
Level of Instruction: Basic

CE Credit for this course has expired.

This webinar is part 1 of a three-part series exploring how measuring tumor mutational burden can improve patient care.

For more information on this series, please go here.

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