STK11 and KEAP1 Mutations in Lung Cancer
This course contains the webinar recording, PDF handout, pre- and post- knowledge check questions, and continuing education credit (CME and CMLE).
This webinar is part 20 of the Emerging and Evolving Biomarkers Series.
Description:
STK11 and KEAP1 mutations have emerged as predictive biomarkers of immunotherapy resistance in non-small cell lung cancer. This webinar reviews the biology of STK11 and KEAP1, offers practical guidance in laboratory testing, and provides evidence for application in clinical practice.
Learning Objectives:
- Explain the biology of STK11 and KEAP1 and their prevalence in lung cancer.
- Interpret the pathogenicity of STK11 and KEAP1 mutations from sequencing results.
- Discuss the implications of STK11 and KEAP1 mutations in therapy selection for patients with lung cancer.

Speaker:
Biagio Ricciuti, MD, PhD
Dana-Farber Cancer Institute
Moderator:
Fei Dong, MD
Stanford University
Duration: 1 Hour
Date Recorded: June 26, 2025
Continuing Education Credit Information
CME credit: 1.0CMLE credit: 1.0
Last day to claim credit: December 31, 2027
Accreditation Statements
AMA PRA Category 1 Credit(s)™
This
activity has been planned and implemented in accordance with the
Essential Areas and policies of the Accreditation Council for Continuing
Medical Education through the joint providership of American Society
for Clinical Pathology (ASCP) and Association for Molecular Pathology
(AMP). The American Society for Clinical Pathology (ASCP) is accredited
by the ACCME to provide continuing medical education for physicians.
The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
CMLE
This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours of CMLE credit. ASCP CMLE credit hours are acceptable for the
ASCP Board of Certification (BOC) Certification Maintenance Program (CMP). CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements
for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity.
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