AMP Certificate Program: Pharmacogenomics: Genes, Drugs, and Genotyping: AMP Pharmacogenomics Guidelines

This AMP certificate program  contains about 4.5 hours of lecture content, the associated pdf slides of the lectures, pre-tests, and post-lecture tests, additional downloadable resources, and an AMP Certificate of Completion.

CME and CMLE credits are not available for this certificate program.

Pharmacogenomics is an important and evolving area of medical testing that combines pharmacology and genomics to identify genomic variability that can affect individual drug response. There is a need in the general medical and laboratory communities to understand the fundamentals of pharmacogenomics and the impacts of molecular testing on optimizing drug selection. This certificate program is intended to provide an introduction to pharmacogenomics and to review AMP expert consensus recommendations for standardization of alleles for clinical pharmacogenomic genotyping assays.

The course contains a pre-test to test your baseline knowledge of the content. It is then followed by presentations by subject matter experts and then a post-test after each section to test your knowledge of the content. It also provides additional useful resources including a resource list fill of links that all pharmacogenomics professionals should know and a Molecular in My PocketTM card outlining the Tier 1 and Tier 2 recommended alleles in one handy worksheet. Finally, case study questions at the end will challenge you to implement what you've learned.

Showcase your knowledge by completing the entire course and passing each post-test with a score of 75% or greater and receiving the AMP Certificate of Completion.

Target Audience: Molecular pathologists, residents, laboratory directors, technologists, and others who have some prior exposure to molecular diagnostic testing. Secondary audiences include oncologists, genetic counselors, primary care clinicians, and other health care professionals.

Topics Covered in Certificate Program: For a detailed outline, click here.

  1. Introduction to Pharmacogenetics
  2. Recommendations for Clinical CYP2C19 Genotyping Allele Selection
  3. Recommendations for Clinical CYP2C9 Genotyping Allele Selection
  4. Recommendations for Clinical Warfarin Genotyping Allele Selection
  5. Recommendations for Clinical CYP2D6 Genotyping Allele Selection

Learning Objectives:
  • Use appropriate nomenclature when describing genes and variants involved in Pharmacogenomics (PGx).
  • Describe the application of Association for Molecular Pathology (AMP) PGx Working Group clinical guidelines.
  • Outline the importance of standardizing PGx testing across clinical laboratories
  • Discuss the key considerations of clinical PGx test development, including gene contents, testing methods, and reference materials.
  • Describe and discuss AMP PGx Working Group ‘Tier 1 and 2’ recommended alleles for CYP2C19, CYP2C9, warfarin sensitivity genes, and CYP2D6.

Duration: ~4.5 hours of video
AMP Certificate Program Launched: January 18, 2022

AMP Certificate of Completion Credit available: 4.5 hours
Last day to complete the course: December 31, 2024

CME and CMLE credits are not available for this certificate program.

Watch the excerpt from the welcome message from the content director.



Victoria Pratt, PhD, FACMG 
Content Director

Karen Weck, MD, FACMG
Planning Committee

Yuan Ji, PhD, MBA, FACMG
Planning Committee

Reynold C. Ly, PhD
Planning Committee

Jeffrey Kleinberger, MD, PhD
Planning Committee
T&E Representative

Stuart A. Scott, PhD, FACMG
Ann Moyer, MD, PhD
Thanks to all who contributed to the project including the AMP Training & Education Committee for their support and careful review.

Supported by an educational grant from Illumina . No personally-identifiable information regarding you is provided to any grant supporters.


CME and CMLE credits are not available for this certificate program.

Note: Members of AMP can access this webinar at no cost. Join the AMP Family!

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No digital files may be reproduced or transmitted in any form, by any means, electronic or mechanical. By purchasing a product, you agree to not share any of the course materials, including videos, downloadable slide presentations, outlines, manuscripts, etc. without explicit and written permission from AMP.