Emerging and Evolving Biomarkers: KRAS: Recent Findings, Laboratory Considerations, and Clinical Implications

Craig Mackinnon, MD, PhD

The University of Alabama at Birmingham


Kurtis Davies, PhD
University of Colorado, Anschutz Medical Campus

This webinar is part 7 of the Emerging and Evolving Biomarkers Series

CME/CMLE Credit is not available for this webinar.


KRAS plays an important role in regulating cell growth and proliferation. It is commonly mutated in cancer, and recently targeted therapy is available for patients whose tumors harbors specific KRAS variants. This presentation will describe the role of KRAS in cellular signal transduction pathways, discuss different methods for testing KRAS for genetic variants, and review the clinical implications for cancers with KRAS mutation.

Learning Objectives:

  • Describe the KRAS signaling pathway
  • Describe molecular testing methods utilized to detected variants in the KRAS gene
  • Explain the clinical significance of KRAS variants

This program has been supported through educational grant funding provided by Amgen and Loxo Oncology at Lilly (for further information concerning Lilly grant funding visit www.lillygrantoffice.com.) Supporting companies had no control over its content. No personally-identifiable information regarding you is provided to any grant supporters.

Recording Date: October 12, 2021
Duration: 55 min
Level of Instruction: Basic

AMP is pleased to collaborate in the Immunotherapy Collaborative of Oncology Networked Communities, IC-ONC.  IC-ONC is a global information network in which multidisciplinary healthcare providers, responsible for treating patients with cancer, are connected via education.  

Please be sure to visit www.ic-onc.org to learn more about the collaborative and all it has to offer.

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