AMP Horizons Series: Whole Genome Sequencing for Clinical Cancer Diagnostics

CME and CMLE credits are not available for this course.

Cytogenetic evaluation of AML and MDS has been the mainstay of clinical risk assessment for over 40 years.  While effective for risk-stratification, cytogenetics requires the culture of live cells and provides limited resolution to resolve complex genomic events. Whole genome sequencing, WGS, is capable of unbiased genomic evaluation from DNA but has been considered too expensive and too complicated, for clinical use.  In this webinar we will discuss recent advances that have made WGS feasible in the clinical setting, how WGS data can be used for the comprehensive genomic assessment of AML and MDS patients, and how WGS could be implemented for the evaluation of other cancer types. 

Learning Objectives:

• Describe how cytogenetics and molecular testing plays a role in the diagnosis and management of myeloid disorders such as AML.
• Identify key barriers to using whole genome sequencing (WGS) in the clinical setting.
• Describe benefits of WGS over conventional genomic testing in myeloid malignancies.
• Identify other areas of molecular diagnostics where WGS could be applied.

Speaker: Eric Duncavage, MD Washington University School of Medicine	Moderator: Nathanael G. Bailey, MD Chair, T&E Committee University of Pittsburgh Medical Center

Continuing Education Credit Information

CME and CMLE credits are not available for this course.

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