AMP Horizons Series: DNA Methylation Profiling in Clinical Diagnostics of Brain Tumors


This webinar outlines the principles and applications of DNA methylation profiling in diagnostics of cancer, particularly in brain tumors. The webinar reviews practical aspects of introducing, validating and performing DNA methylation testing by EPIC arrays in a clinical laboratory.

Learning Objectives:

  • Identify the pre-analytical, analytical and post-analytical variables affecting DNA methylation array performance
  • Identify the design and information input for machine learning
  • Identify the effect of various mutation drivers on DNA methylation signature in cancer
  • Understand the principle of the assay and variables affecting the performance

Matija Snuderl, MD
NYU Langone Health
New York, NY
Alanna Church, MD
Boston Children's Hospital
Boston, MA
Duration: 1 hr
Level of Instruction: Intermediate
Date Recorded: December 3, 2020

Planned and coordinated by the Training and Education Committee

Continuing Education Credit Information

CME credit: 1.0
CMLE credit: 1.0 
Last day to claim credit: March 20, 2022

Accreditation Statements
AMA PRA Category 1 Credit(s)™
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Society for Clinical Pathology (ASCP) and Association for Molecular Pathology (AMP). The American Society for Clinical Pathology (ASCP) is accredited by the ACCME to provide continuing medical education for physicians.

The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours of CMLE credit. ASCP CMLE credit hours are acceptable for the ASCP Board of Certification (BOC) Certification Maintenance Program (CMP). CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity. 

Note: Members of AMP can access this webinar at no cost. Join the AMP Family!

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