AMP Horizons Series: Sample Collection and Molecular Diagnosis of SARS-CoV-2 Infection


This presentation will describe what is known regarding optimal sampling for initial diagnosis of infection with the SARS-CoV2 virus, based upon both published data and unpublished data that has previously been provided to FDA.  Particular attention will be given to sampling devices and locations, including nasopharynx, mid-turbinate, nose, saliva and sputum, as well as specimen transport.  In addition, the presentation will describe relationships between molecular test results and the clinical and virological course of covid19, together with the impact of these factors on CDC recommendations for patient management and their implications for test utilization management.

Learning Objectives:

  1. Describe the strength and weakness of sampling from various anatomic sites for detection of SARS-CoV-2 by molecular methods.
  2. Describe the time course for molecular detection of SARS-CoV-2 virus and the relationship to recovery of productive virus from symptomatic individuals.
  3. Describe current recommendations for isolation of symptomatic individuals infected with SARS-CoV-2.
Timothy J. O’Leary, MD, PhD
Yuan-Po Tu, DVM, MD
Yassmine Akkari, PhD

Duration: 1 hr
Level of Instruction: Intermediate
Date Recorded: May 14, 2020
Planned and coordinated by the Training and Education Committee

Continuing Education Credit Information

CME credit: 1.0
CMLE credit: 1.0 
Last day to claim credit: March 20, 2022

Accreditation Statements
AMA PRA Category 1 Credit(s)™
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Society for Clinical Pathology (ASCP) and Association for Molecular Pathology (AMP). The American Society for Clinical Pathology (ASCP) is accredited by the ACCME to provide continuing medical education for physicians.

The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours of CMLE credit. ASCP CMLE credit hours are acceptable for the ASCP Board of Certification (BOC) Certification Maintenance Program (CMP). CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity. 

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