Molecular Biomarkers for the Evaluation of Colorectal Cancer

Please note that this webinar was recorded in 2017. All AMPEDTM content is reviewed and approved annually by the Training & Education Committee as relevant and accurate, but new data may now be available and new studies may have since been published.

AMP Education is constantly updating these educational offerings, so keep checking back at for new content, content updates, and information on cutting-edge molecular pathology research and applications.


In this webinar, Antonia Sepulveda provides an overview of the American Society of Clinical Pathology (ASCP), College of American Pathologists (CAP), Association for Molecular Pathology (AMP), and American Society of Clinical Oncology (ASCO)'s evidence-based practice guideline on molecular marker testing for patients with colorectal carcinoma that identifies opportunities for improving patient outcomes.

The guideline addresses a wide range of molecular markers appropriate for testing in patients with early and advanced colorectal cancer which aids in establishing standard molecular marker testing to help guide targeted therapy decisions and advance personalized care for colorectal cancer patients.

Learning Objectives:

  • Discuss the recently published molecular testing guidelines for colorectal cancer.
  • Describe current laboratory practice guidelines for the use and performance of molecular testing in the evaluation of colorectal cancer.
  • Evaluate prognosis and prediction of response to therapies for the following markers: KRAS, NRAS, BRAF, PIK3CA, PTEN, DNA mismatch repair/microsatellite instability.

Practice Guideline Available Here

Speaker: Antonia R. Sepulveda MD, PhD
Host: Anna Yemelyanova, MD
Duration: 1.0 hr
Level of Instruction: Basic
Recording Date: March 31, 2017

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