Tumor Mutational Burden: Result Reporting and Application to Improve Patient Care


Ahmet Zehir, PhD    


Jonathan Nowak, M.D.,Ph.D.

This webinar is a recorded presentation of a live broadcast and includes the presentation, handout, and the audience QA.


As tumor mutational burden (TMB) is gaining traction as a predictive biomarker for immunotherapy, the challenge of reporting TMB back to the treating oncologists and patients in an informative way still exists. In this webinar, we will discuss strategies of implementing TMB in the clinical laboratory, how different TMB values reported from various assays compare to each other, and how to communicate the results in a clear way.

Learning Objectives:

  • Describe challenges and opportunities in the implementation of TMB testing in the clinical laboratory. 
  • Discuss the various ways by which TMB can be reported back to the clinicians and patients

Recording Date: September 26, 2018
Duration: 1 hr
Level of Instruction: Basic
CME/CMLE credit: 1.00 hour
SAM credit: 1.00 hour
Last Day to Purchase Credit: December 31, 2020

How to claim credit: 

To earn CME/CMLE credit, all learners must watch the webinar and then complete the online survey.

AMA PRA Category 1 Credit(s)™

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of American Society for Clinical Pathology (ASCP) and Association for Molecular Pathology (AMP). The American Society for Clinical Pathology (ASCP) is accredited by the ACCME to provide continuing medical education for physicians.

The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

This continuing medical laboratory education activity is recognized by the American Society for Clinical Pathology for 1.0 hours of CMLE credit. ASCP CMLE credit hours are acceptable for the ASCP Board of Certification (BOC) Certification Maintenance Program (CMP). CMLE credit hours meet the continuing education requirements for the ASCP Board of Certification Credential Maintenance Program (CMP) and state relicensure requirements for laboratory personnel. Participants should claim only the credit commensurate with the extent of their participation in the activity.

To earn SAM credit, all learners must watch the webinar, achieve a minimum score of 80% on the online quiz, and complete an online survey.

This course is approved by the American Board of Pathology for 1.0 SAM credits.Physicians should only claim credit commensurate with the extent of their participation in the activity. Participants must successfully complete the online modular exams (answering at least 80% of the questions in a topic module correctly).

* You may not submit SAMs and CME/CMLE credit for the same content.

This webinar is part 3 of a three-part series exploring how measuring tumor mutational burden can improve patient care.

For more information on this series, please go here.

This program has been supported through an educational grant from Bristol-Myers Squibb.

Note: Members of AMP can access many of the webinars at no cost or a deep discount. Join the AMP Family!

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