Tumor Mutational Burden: Best Practices to Address Clinical and Technical Challenges
Jonathan Nowak, M.D.,Ph.D.
Jeremy Segal, MD, PhD
This webinar is a recorded presentation of a live broadcast and includes the presentation, handout, and the audience QA.
Please note that this content was created in 2018. In the time since this material was posted, there may have been additional developments, advancements, and/or more current publications in this field.
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This webinar will cover the methodology for calculating tumor mutational burden (TMB) and will review technical considerations that can impact TMB calculation. The utility of detecting the underlying mutational processes that determine a tumor's mutational burden will also be discussed. The course will cover an overview of immunotherapy drugs, targets, and tumor types for which TMB has been used as a biomarker.
- Describe laboratory and bioinformatic factors that can influence TMB calculation.
- Describe the underlying mutational processes that give rise to a tumor's mutational burden
Recording Date: August 28, 2018
Duration: 1 hr
Level of Instruction: Basic
CE Credit for this course has expired.
This webinar is part 2 of a three-part series exploring how measuring tumor mutational burden can improve patient care.
For more information on this series, please go here.
This program has been supported through an educational grant from Bristol-Myers Squibb.
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