This product includes the webinar and SAM credit


This presentation summarizes the findings of the Association for Molecular Pathology Chronic Myeloid Neoplasm Working Group. Chronic myeloid neoplasms (CMNs) are defined as a complex group of hematopoietic disorders, encompassing myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPNs), the overlap entities (MDS/MPNs), and systemic mastocytosis. The goal of this group was to distill the vast amounts of literature on the mutational profiles of the CMNs into high impact information that would aid molecular pathologists in the development of next generation sequencing (NGS) myeloid panels. This work identifies 34 genes as the minimum recommended testing list and provides information on the frequency of these genes in the various CMNs as well as their prognostic and therapeutic import. In addition, the findings highlight the recurrent patterns of mutational clonal evolution in these patients, uncovering critical insight into the biology of these neoplasms.

Practice Guideline Available Here

Speaker: Annette S. Kim, MD, PhD

Moderator: Todd W. Kelley, MD

Duration: 1 hr

Level of Instruction: Intermediate

Last day to purchase course and claim credit: July 19, 2021

Maximum SAM credit available: 1.0

How to claim credit: To earn SAM credit, all learners must watch the webinar, achieve a minimum score of 80% on the online quiz, and complete an online survey. To access the quiz, click "Submit credit" on the course homepage or click on "My Credit" on the menu to the left and then "submit credit" for the appropriate course.

This course is approved by the American Board of Pathology for 1.0 SAM credits.Physicians should only claim credit commensurate with the extent of their participation in the activity. Participants must successfully complete the online modular exams (answering at least 80% of the questions in a topic module correctly).

SAM questions edited by: Alan Brown, MD and Kristin Karner, MD

* You may not submit SAMs and CME/CMLE credit for the same content.

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Course Information
Course Date:
July 19, 2018
Course Objectives
  • List the four main pathways in which there are recurrent mutations in chronic myeloid neoplasms.
  • Characterize the common patterns of mutations seen in the chronic myeloid neoplasms.
  • Deconstruct the patterns of clonal evolution seen in the chronic myeloid neoplasms.
Mutational Pattern Recognition in Chronic Myeloid Neoplasms (CMNs)
Individual topic purchase: Selected
American Board of Pathology
Self-Assessment Module: 1.00
Kim (+SAM)
AMP Regular Member: $0.00
AMP Technologist Member: $0.00
AMP Associate Member: $0.00
Non-member Price: $215.00