This webinar is a recorded presentation of a live broadcast and includes the presentation, handout, and the audience QA. If you would like continuing education credit for the webinar, click on the links in the table below to access the webinar + CME/CMLE or webinar + SAM


Jonathan Nowak, MD, PhD 


Jeremy Segal, MD, PhD


Description: This webinar will cover the methodology for calculating tumor mutational burden (TMB) and will review technical considerations that can impact TMB calculation. The utility of detecting the underlying mutational processes that determine a tumor's mutational burden will also be discussed. The course will cover an overview of immunotherapy drugs, targets, and tumor types for which TMB has been used as a biomarker.

Duration: 1 hr

Level of Instruction: Basic

This webinar is part 2 of a three-part series exploring how measuring tumor mutational burden can improve patient care. If you'd like more information about the series go here.

This program has been supported through an educational grant from Bristol-Myers Squibb.

Click on the links below to purchase continuing education credit.

Credit Type Number of Credit Hours Click on link to purchase:

Purchase Webinar + CME/CMLE

(Free for all)

SAM 1.0

Purchase Webinar + SAM

(Free for all)

Continuing Education Credit must be purchased and claimed by December 31, 2020


* You may not submit SAMs and CME/CMLE credit for the same content.

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Course Information
Course Date:
August 28, 2018
Course Objectives
  • Describe laboratory and bioinformatic factors that can influence TMB calculation.
  • Describe the underlying mutational processes that give rise to a tumor's mutational burden
Pre-Test for TMB: Best Practices for Clinical and Technical Challenges
Tumor Mutational Burden: Best Practices to Address Clinical and Technical Challenges
Post-Test for TMB: Best Practices to Address Clinical and Technical Challenges

Thank you for watching "Tumor Mutational Burden: Best Practices to Address Clinical and Technical Challenges". This quiz will gauge your understanding of the material now that you have watched the webinar. You may only take the test once, but please note that an explanation of the answers will be provided to you after you submit your quiz.  

After you have reviewed the material, you may proceed to the question and answer portion of the webinar by clicking "QA Session" on the navigation tab to the left.

Good luck and thank you for your participation.

QA Session
Individual topic purchase: Selected
Nowak Presentation
AMP Regular Member: $0.00
AMP Technologist Member: $0.00
AMP Associate Member: $0.00
Non-member Price: $0.00